Gregg Semenza, Department of Pediatrics, Medicine, Oncology, and Radiation Oncology, Johns Hopkins University School of Medicine, Baltimore, USA
Dr. Semenza received an A.B. degree in Biology magna cum laude from Harvard College; M.D. and Ph.D. degrees from the University of Pennsylvania; pediatrics residency training at Duke University Medical Center; and postdoctoral training in Medical Genetics at the Johns Hopkins University School of Medicine, where he has spent his entire career. He is currently the C. Michael Armstrong Professor at Johns Hopkins with appointments in Pediatrics, Medicine, Oncology, Radiation Oncology, Biological Chemistry, and Genetic Medicine. Since 2003 he has served as founding Director of the Vascular Program in the Johns Hopkins Institute for Cell Engineering. Dr. Semenza currently serves on the editorial boards of Antioxidants and Redox Signaling, Cancer Research, Cardiovascular Research, Journal of Clinical Investigation, Molecular and Cellular Biology, Molecular Cancer Therapeutics, and Oncogene. He is Editor-in-Chief of the Journal of Molecular Medicine. He has been elected to the Society for Pediatric Research, American Society for Clinical Investigation, Association of American Physicians, and the National Academy of Sciences USA. Dr. Semenza is a recipient of the 2010 Canada Gairdner International Award and the 2012 Grand Prix Lefoulon-Delalande. Dr. Semenza’s laboratory identified hypoxia-inducible factor 1 (HIF-1), a protein that allows metazoan cells to respond to changes in oxygen availability. The purification of HIF-1 in 1995 opened the field of oxygen biology to molecular analysis and has revealed major roles for HIF-1 in many evolutionary, developmental, physiological, and pathological processes.
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