Cell symposia : Angiogenesis, Metabolic Regulation, and Cancer Biology in association with VIB

Conference Program

Click here to download the program PDF

Click here to download the poster program

Friday 6th July
11.00 Registration
Foyer - Pieter de Somer Auditorium
14.30 Welcome and Introduction
Pieter de Somer Auditorium
Session I– Molecular Insights into Vessel Branching
Session Chairs: Celeste Simon and Daniel Wainstock
14.45 – 15.40 KEYNOTE: VEGF-B: A coronary growth factor and a metabolic regulator
Kari Alitalo
Helsingin Yliopisto, Finland
15.40 - 16.15 Organ-specific endothelial responses to systemic signals
Luisa Iruela-Arispe
University of California, Los Angeles, USA
16.15 – 16.30 Short Talk: Endothelial tip and stalk cell selection depends on integration of BMP-Smad and Notch signaling
An Zwijsen
VIB and Katholieke Universiteit Leuven, Belgium
16.30 – 17.00 Coffee
Foyer–Pieter de Somer Auditorium
17.00 – 17.35 Cell competition and cooperation during sprouting angiogenesis
Holger Gerhardt
Cancer Research UK London Research Institute, UK and VIB, Belgium
17.35 – 18.10 Controlling the dynamics of vascular growth by FOXO and sirtuin pathways
Michael Potente
Goethe-University Frankfurt am Main, Germany
18.10 – 18.25 Poster Teasers
18.30 Drinks Reception   
Alma 2 Restaurant                                                                       
Saturday 7th July
Session II– Vessel Abnormalities and Metabolism
Session Chairs: Adrian Harris and Jo Bury
09.00 – 09.35 Targeting endothelial metabolism: Principles and strategies
Peter Carmeliet
VIB and Katholieke Universiteit Leuven, Belgium
09.35 – 10.10 Intercellular metabolic regulation of molecular and functional phenotype
Joseph Loscalzo
Harvard Medical School and Brigham and Women's Hospital, Boston, USA
10.10 – 10.25 Short Talk: Inhibition of the p110α isoform of PI 3-kinase in the stroma dampens tumor growth by reducing blood vessel size
Mariona Graupera
Barts Cancer Institute, Queen Mary University of London, UK
10.25 – 10.50 Coffee   
Foyer –Pieter de Somer Auditorium
10.50 – 11.25 Sphingosine 1-phosphate signalling
Timothy Hla
Weill Medical College, Cornell University, USA
11.25 – 12.00 Finding the mechanism that enables the provision of nutrients to proliferating cells
Salvador Moncada
University College London, UK and VIB, Belgium
12.00 – 13.00 Lunch    
Alma 2 Restaurant
13.00 – 15.00 Poster Session I
Session III– Cancer Metabolism                                                         
Session Chairs: Douglas Hanahan and Nikla Emambokus
15.00 – 15.55 KEYNOTE: Targeting cancer metabolism: Why don't elephants get cancer?
Chi Van Dang
Abramson Cancer Center, University of Pennsylvania, USA
15.55 – 16.30 A role for p53 in the regulation of metabolism
Karen Vousden
The Beatson Institute for Cancer Research, Glasgow, UK
16.30 – 16.45 Short Talk: Candidate Roles for Protein Succination in Altered Metabolism and Oncogenesis
Ming Yang
University of Oxford, UK
16.45 – 17.15 Coffee
Foyer–Pieter de Somer Auditorium
17.15 – 17.50 Mitochondrial metabolism and tumor cell growth
Ralph DeBerardinis
University of Texas - Southwestern Medical Center at Dallas, USA
17.50 – 18.25 Regulation of breast cancer metastasis by hypoxia-inducible factor 1
Gregg Semenza
Johns Hopkins University School of Medicine, Baltimore, USA
19.45 “Meet the Speakers” Dinner (Optional)                           
Sunday 8th July
Session IV– Feedback Regulation of Angiogenesis                                                         
Session Chairs: Timothy Hla and Ann Cheung
09.00 – 09.35 Negative feedback control of VEGF in tumor invasion
Gabriele Bergers
University of California, San Francisco, USA
09.35 – 10.10 Vascular and metabolic resistance mechanisms to antiangiogenic therapy
Adrian Harris
Weatherall Institute of Molecular Medicine, University of Oxford, UK
10.10 – 10.25 Short Talk: Notch1: A metabolic gatekeeper of the endothelial cell cycle
Katrien De Bock
VIB, Leuven, Belgium
10.25 – 10.50 Coffee
Foyer –Pieter de Somer Auditorium
10.50 – 11.25 MicroRNAs in angiogenesis signaling
Stefanie Dimmeler
University Frankfurt, Germany
11.25 – 12.00 Hypoxia, metabolism, and tumor progression
M. Celeste Simon
University of Pennsylvania, USA
12:00 – 12.35 Linking oncogenic activation to myeloid cell recruitment and tumor angiogenesis
Napoleone Ferrara
Genentech, USA
12.35 – 13.30 Lunch
Alma 2 Restaurant
13.30 – 15.30 Poster Session II
Alma 2 Restaurant
Session V– Stromal Plasticity and Tumor Microenvironment                       
Session Chairs: Luisa Iruela-Arispe and Peter Carmeliet
15.30 – 16.05 Interfaces between tumor angiogenesis and invasion
Douglas Hanahan
Institut Suisse de Recherche Experimentale sur le Cancer (ISREC), Switzerland
16.05 – 16.20 Short Talk: Endothelial cells as a niche for the differentiation and functional polarization of M2 macrophages
Huanhuan He
University of California-Los Angeles, USA
16.20 – 16.50 Coffee
Foyer Pieter de Somer Auditorium
16.50 – 17.25 Tumor-associated macrophages
Michele De Palma
Institut Suisse de Recherche Experimentale sur le Cancer (ISREC), Switzerland
17.25 – 17.40 Short Talk: Regulatory roll of mir-27a in VEGF induced endothelial differentiaion of breast cancer stem-like cells
Ling Lin
Sun-Yat-Sen University, Guangzhou, People’s Republic of China
17.40 – 18.15 Transdifferentiation of Tumor Cells to Endothelial Cells
Inder Verma
The Salk Institute for Biological Studies, La Jolla, USA
18.15 Closing Remarks

Organized by

Cell Symposia - Elsevier

Sponsor/Exhibitor

VIB

Jackson Immuno Research Europe Ltd.

Seahorse Bioscience

Medicyte

abcam

PerkinElmer

Supporting Publications

Cancer Cell
Cell Metabolism
Developmental Cell